PROGRESS TOWARDS THE ELUSIVE MASTITIS VACCINES

Progress towards the Elusive Mastitis Vaccines

Mastitis is a major problem in dairy farming.Vaccine prevention of mammary bacterial infections is of particular interest in helping to deal with this issue, all the more so as antibacterial drug inputs in dairy farms must be reduced.Unfortunately, the effectiveness of current vaccines is not satisfactory.In this review, we examine the possible rea

read more


Plasmodium falciparum-mediated induction of human CD25Foxp3 CD4 T cells is independent of direct TCR stimulation and requires IL-2, IL-10 and TGFbeta.

CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) regulate disease-associated immunity and excessive inflammatory responses, and numbers of CD4(+)CD25(+)Foxp3(+) Tregs are increased during malaria infection.The mechanisms governing their generation, however, remain to be elucidated.In this study we investigated the role of commonly accepted factors

read more